Open Philanthropy recommended a grant of $206,613 to UC Davis to support a trial led by Koen Van Rompay of an HSP90 inhibitor as a possible treatment for Zika infections in rhesus macaque monkeys. The results of the trial could have implications for the use of HSP90 inhibitors as antiviral treatments in humans. This funding is part of Open Philanthropy's science team’s effort to explore chaperone inhibitors as broad spectrum, host-directed antiviral drugs.
This falls within Open Philanthropy's work on scientific research, specifically within its interest in science supporting biosecurity and pandemic preparedness.
The grant amount was updated in June 2020.